CAST papers are the foundation of CAST’s science communication work. Developed by expert-led task forces, these peer-reviewed publications translate agricultural science into trusted insights that inform policy, guide public understanding, and fuel CAST programs, dialogues, and educational initiatives.

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Gains Foregone by Going GMO Free: Potential Impacts on Consumers, the Environment, and Agricultural Producers

Task Force Chairs
University of Delaware
Authors
Purdue University
Purdue University
University of California, Davis
Washington State University
Purdue University
University of Alberta
University of Saskatchewan
Abstract
This paper examines the societal, environmental, and economic implications of eliminating genetically modified organisms (GMOs) from agricultural production systems. GMOs have enabled significant advancements in food security, yield stability, pest and disease management, and environmental sustainability over the past three decades. The authors synthesize evidence demonstrating that GMO crops reduce pesticide use, lower toxicity exposure, conserve land through higher yields, and support conservation tillage practices that enhance soil health and reduce greenhouse gas emissions. Conversely, removing GMO traits would increase global land‑use pressure, raise pesticide applications, elevate food prices, and reduce farmer income—effects that would be particularly harmful for low‑income consumers and developing regions. The analysis highlights how GMOs contribute to human health through reduced mycotoxin levels and emerging biofortified crops, such as Golden Rice, which address micronutrient deficiencies. Additionally, the paper identifies how regulatory delays and trade barriers restrict innovation and contribute to global welfare losses. Overall, the findings indicate that foregoing GMO technology would impose substantial economic, environmental, and public‑health costs, underscoring the importance of science‑based policy frameworks that enable continued innovation and adoption of genetically engineered and gene‑edited crops. [QTA2021-2-GMO-Free-1 | PDF]
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Reviewers
PG Economics Ltd
University of Bonn
University of Adelaide
CAST Liaisons
Elanco Animal Health
Orrville Veterinary Clinic
Translators